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Chronic CO Poisoning:

Bronstein Dual Case Study:

Neurobehavioral findings in two cases of chronic low level carbon monoxide poisoning

Bronstein, A.C., Kadushin, F.S., Teitelbaum, D.T.


Veterinary & Human Toxicology, 29 (6), pg. 479 (abstract only).

The subtle central nervous system effects of chronic low level carbon monoxide (CO) poisoning are often not detected by standard neurological or neuroradiological techniques. Diagnosis and assessment of cognitive and emotional functioning requires complete neurobehavioral examination. Two patients with chronic CO toxicity from faulty home furnaces were evaluated: Patient #1 - 30 year old white female librarian and Patient #2 - 58 year old white female writer. Reported subjective symptoms included: headaches, fatigue, memory loss, concentration problems, incoordination and emotional lability. These patients demonstrated impaired learning, memory, mental flexibility, motor speed, and grip strength. Psychological interviews revealed depression, increased irritability and subjective feelings of personality changes. Findings were consistent with subcortical and frontal dysfunction as seen in patients with acute CO poisoning symptoms. Work-up of patients with presumed CO exposure should include complete neurobehavioral assessment.

Location of Authors:
Western Institute of Neurotoxicology, Denver, Colorado 80203

Presented at:
1987 Meeting of the American Academy of Clinical Toxicology, American Association of Poison Control Centers, American Board of Medical Technology, Canadian Association of Poison Control Centers, Vancouver, British Columbia, Canada, Sept. 27 - Oct. 2, 1987.

...... last changed 06/21/01

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