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CO and Risk




Carbon Monoxide Poisoning

Special Groups at Risk:

Table 1. Prenatal CO Exposures - Animal Studies - Immediate and at-Birth Effects:

Species Carbon Monoxide Exposure Effects
mouse high level CO, few minutes, repeatedly abortions, resorptions, abnormal growth of survivors
mouse moderate level CO, many days increased fetal mortality
mouse moderate level CO, many days, decreased
protein diet
decreased fetal body wt., increased death & resorption of fetuses, brachygnathia,
microsomia, microcephaly, protruding tongue, open mouth, open eyes
mouse moderate level CO, many days increased resorptions, decreased body wt. & crown-rump length, increased skeletal anomalies
rat high level CO, few minutes, repeatedly decreased litter size, decreased preweaning survival
rat high level CO, few hours, repeatedly absorptions, stillbirths, skeletal anomalies, decreased fetal body wt., decreased
crown-rump length
rat low level CO, many days, decreased oxygen decreased body wt., increased brain wt., decreased lung wt., decreased brain serotonin
rat high level CO, few hrs, repeatedly decreased fetal body wt.
rat moderate level CO, many days increased placental wt., decreased fetal body wt.
rat high level CO, few hrs, repeatedly decreased fetal body wt., decreased placental wt.
rabbit moderate level CO, many days increased fetal body wt., & crown-rump length
rabbit high level CO, few minutes, many days increased fetal deaths
pig moderate-high level CO, for several days increased stillbirths


Note: For more detailed information, contact the webmaster (E-mail = dpenney@cmb.biosci.wayne.edu), or consult the book Carbon Monoxide, 1996, by David G. Penney, Ph.D.


...... last changed 06/27/02



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